Clinical Protocols
To view the research protocols for a particular specialty, select the specialty from the menu below. Where the studies below are listed in ClinicalTrials.gov and are actively recruiting patients, a link is provided to the corresponding site.
Cardiothoracic
Visit the Cardiothoracic research page for more information.
General Surgery
Visit the General Surgery research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| John Alverdy | Effect of Intestinal Pseudomonas Aeruginosa on the Critically Ill Patient | Dr. Alverdy's lab |
| Peter Angelos | Long-Term Outcomes of Endocrine Surgery Patients New Pediatric Surgeons and the Informed Consent Process |
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| Alessandro Fichera | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Intravenous (IV) Ulimorelin Administered Post-Operatively to Accelerate Recovery of Gastrointestinal (GI) Motility in Subjects Who Have Undergone Partial Bowel Resection (Protocol: TZP 101-CL-P008) A Phase III Prospective Randomized Trial Comparing Laparoscopic-Assisted Resection versus Open Resection for Rectal Cancer A Retrospective Review of Patient Outcomes in Robotic versus Laparoscopic Surgery for Inflammatory Bowel Disease Colon and Rectal Surgery Clinical Research Screening Protocol Perianal Dermatitis in Patients After Ileal Pouch Anal Anastomosis for Ulcerative Colitis Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for UT2uNo Rectal Cancer (Z6041) Surgical Management of Colorectal Pathology: A Retrospective Review of Laparoscopic Surgery Versus Open Abdominal Surgery on Patient Outcome |
Dr. Fichera's clinical research |
| Nora Jaskowiak | A Pilot Study of Chemo-prevention of Green Tea in Women with Ductal Carcinoma in Situ (DCIS) NSABP-P-2: Study Comparing Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer |
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| Edwin Kaplan | Investigation of Primary Hyperparathyroidism in Young Populations at the University of Chicago Hospitals | |
| Vivek Prachand | Surgical Management of Obesity: A Retrospective Cohort Study of Patients Treated with Bariatric Surgery Bariatric Outcomes Longitudinal Database (BOLD) |
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| Kevin Roggin | Evaluation of KOC in Pancreatic Cyst Fluid Laparoscopic Resections for Gastric GIST Molecular Determinants of Malignancy in Pancreatic Cystic Neoplasms Percutaneous Cholecystostomy Pilot study to assess the safety and efficacy of percutaneous diagnostic peritoneal lavage to sample peritoneal cytology in patients with advanced gastric cancer Preoperative Predictors of Mortality, Morbidity and Quality of Life in Patients Undergoing Pancreaticoduodenectomy |
Neurosurgery
Visit the Neurosurgery research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Issam Awad | Inflammatory and Signaling Pathways in Resected Cerebrovascular Malformations (CVMs) | |
| David Frim |
Feasibility Study of the Medtronic InSite ICP Monitoring System (Medtronic Protocol 0101-Revision B) |
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| Javad Hekmatpanah | A Retrospective Chart Review of Patients Undergoing Surgery for CNS Tumors: Trends and Outcomes Head Injury in Abused and Neglected Children Magnetic Resonance Anatomic Brain Imaging as a Guide to Neurosurgical Landmarks |
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| Maciej Lesniak |
A Phase IIa Study of ADV-TK + Valacyclovir Gene Therapy in Combination with Standard Radiation Therapy for Malignant Gliomas |
Dr. Lesniak's lab |
| Catherine Ojakangas | Cerebral Mechanisms of Human Skills Learning Comparison Study: Deep Brain Stimulation in VIM and cZI for the Treatment of Tremor due to Multiple Sclerosis Cortical and Basal Ganglia Function During Motor Learning in Movement Disorders Outcomes Study: Deep Brain Stimulation in the cZI for the Treatment of Tremor due to Multiple Sclerosis |
Dr. Ojakangas' lab |
| Ben Roitberg | Spine Outcomes Study |
Ophthalmology & Visual Sciences
Visit the Ophthalmology research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Dingcai Cao | Alcohol Effects on Visual Processing in At-Risk Social Drinkers Psychophysical Studies of Retinal Function, Perception and Decision Making Rod and Cone ERGs Under Mesopic Light Levels |
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| Seenu Hariprasad | A Multicenter Randomized Study Evaluating Dosing Regimens for Treatment With Intravitreal Ranibizumab Injections in Subjects With Macular Edema Following Retinal Vein Occlusion A Phase III, Double-Masked, Multicenter, Active Treatment-Controlled Study of the Efficacy and Safety of 0.5 mg and 2.0 mg Ranibizumab Administered Monthly or on an As-Needed Basis (PRN) in Patients with Subfoveal Neoascular Age-Related Macular Degeneration Intravitreal dexamethasone implant (Ozurdex) in the treatment of refractory macular edema secondary to retinal vein occlusions Use of the visual function questionnaire to assess the impact of diabetic macular edema on vision-related quality of life and patient perception of treatment outcomes |
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| Rima McLeod | Consent to receive spiramycin to attempt to prevent congenital toxoplasmosis. (Compassionate use of spiramycin) Pathogenesis, outcome, treatment and prevention of toxoplasmosis. Longitudinal follow-up to determine outcome of toxoplasmosis Pathogenesis, Outcome, Treatment, & Prevention of Congenital Toxoplasmosis. Adults who Provide a Blood Sample by Venipuncture, or Provide a Saliva Sample Obtained by a Self-Collection Kit. (Studies of Immune Responses to T. Gondii and Genetics of Resistance to this Infection) Pathogenesis, Outcome, Treatment, & Prevention of Toxoplasmosis, Treatment with Pyrimethamine and Sulfadiazine for One Year For Treatment of Congenital Toxoplasmosis Pathogenesis, Outcome, Treatment, and Prevention of Toxoplasmosis. Longitudinal Follow-up to Determine Outcome of Untreated Congenital Toxoplasmosis (Historical Patients) Pathogenesis, Outcome, Treatment, and Prevention of Toxoplasmosis. Why Individuals Infected in Utero Become Ill Due to Their Congenital Toxoplasmosis Pregnancy on Immunity to Toxoplasma Gondii Toxoplasmosis -Evaluation of Tissues Use of Intraocular Injection of Antibody to VegF for Treatment of Active Choroidal Neovascular Membranes in Ocular Toxoplasmosis |
Orthopaedic and Rehabilitation Medicine
Visit the Orthopaedic research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Henry Finn | Porous femoral fixation in total hip arthroplasty with short 80 mm stem | |
| Tong-Chuan He | Molecular Biology of Human Bone and Soft Tissue Sarcomas | Dr. He's lab |
| Hue Luu | Molecular basis of metastatic cancer to bone | Dr. Luu's lab |
| David Manning | Surgical Site Infection (SSI) following Total Hip and Revision Hip Arthroplasty | |
| Daniel Mass | Total Wrist Replacement, a Multi-center Study | |
| Bruce Reider | The Role of the Anterior Cruciate Ligament in Proprioception of the Knee |
Otolaryngology/Head & Neck Surgery
Visit the Otolaryngology research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Fuad Baroody | Bacterial Microbiota In The Tonsils Of Children Undergoing Adenotonsillectomy And Normal Controls Image Analysis as a Tool in Diagnosis of Chronic Sinusitis and Tumors of the Paranasal Sinuses Mechanism of action of fluticasone furoate in childhood obstructive sleep apnea syndrome (OSAS) Obstructive sleep apnea in children under 3 years of age: Persistence of disease after adenotonsillectomy |
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| Elizabeth Blair | Analysis of Salivary Gland Tumors Treated at the University of Chicago Identifying Disparities in Head and Neck Squamous Cell Cancer Clinical Trial Participation at the University of Chicago Medical Center |
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| Jacquelynne Corey | A comparison study between cefdinir and amoxicillin/clavulanate in patients with acute sinusitis for assessment of quality of life (QOL) Observational Study of Inhalant Allergen Specific Immunotherapy Survey of Allergy Immunotherapy Post Treatment (SAIPT) The Effect of Intranasal Steroids on the Nasal Cycle Utility of Acoustic Rhinometry to Predict the Outcome of Radiofrequency Ablation of the Turbinates |
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| Robert Naclerio | A Parallel Group Observational Study of the Effects of Allergic Rhinitis on the Nasal/Sinus Microbiome A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial of Topical Allstate in the Prevention of the Signs and Symptoms of the Acute Response to Nasal Allergen Challenge (CETALY0001) Comparison of Intraoperative Bleeding during Endoscopic Sinus Surgery between Patients Receiving Total Intravenous Anesthesia with Propofol and Patients Receiving an Inhalational Anesthetic with Sevoflurane Effect of Prednisone on Peripheral Blood T-cell function (Tregs and Th17) in Patients with Chronic Rhinosinusitis (CRS) Effect of Veramyst and Olopadatine 0.2% Opthalmic Solution Alone and in Combination on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge with Allergen Evaluation of NasoNeb" Delivery of an Intranasal Steroid in the Treatment of Perennial Allergic Rhinitis Nasal Challenge with Antigen The Addition of Vitamin D to Fluticasone Propionate in the Management of Seasonal Allergic Rhinitis |
Dr. Naclerio's research |
| Jayant Pinto |
A Randomized, Clinical Trial of a Novel Immunotherapy for Chronic Sinusitis:Vitamin D |
Dr. Pinto's research |
| Kerstin Stenson | Chart Investigation of Patients with Oral Cavity Cancer Observational Study of Swallowing Function after Treatment of Advanced Laryngeal Cancer Review of Patients Undergoing Salvage Surgery for Recurrent Head and Neck Cancer Tissue Procurement for Head and Neck Cancer Patients Undergoing Surgery or Biopsy |
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| Dana Suskind | Efficacy of LENA System Feedback Reports of Affecting Caregiver Behavior Efficacy of Pilot Project ASPIRE in Affecting Parental Knowledge and Skills Parent Focus Groups for the Development of a Parent-Directed Educational Program on Early Childhood Language Development Thirty Million Words Project: A Feasibility Trial |
Pediatric Surgery
Visit the Pediatric Surgery research page for more information.
Plastic and Reconstructive Surgery
Visit the Plastic Surgery research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Lawrence Gottlieb | Behaviors of Children Ages 15 months to Five Years Around Microwave Ovens Comparison of Two Methods of Negative Pressure Wound Therapy: VAC and G-SUC for Treatment of Surgical or Traumatic Wounds Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: VAC and G-SUC Composite Tissue Allotransplantation in Patients with Solid Organ Allograft Novel use of a V-Y regional advancement flap for closure of anterolateral thigh free flap donor sites Surgical Management of Mediastinitis in the Pediatric Patient |
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| Russell Reid | Distraction Osteogeneis versus Tracheostomy: An analysis of cost and airway improvement Molecular and Immunologic Basis for Craniofacial Suture Biology and Craniosynostosis Reconstruction of complex meningomyelocele wounds: an outcomes study |
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| David Song | A Phase 2, Multicenter, Double-Blind, Placebo-Controlled Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery Aesthetic Breast Conservation Surgery: the development and application of the tumor-breast index Optimizing Outcomes in Breast Conservation Therapy |
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| Lawrence Zachary | Body Contouring in the Post-Bariatric Surgery Patient |
Transplantation
Visit the Transplantation research page for more information.
Urology
Visit the Urology research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Gregory Bales | Sexual Satisfaction of Women with Pelvic Organ Prolapse and Their Male Partners | |
| Scott Eggener | A Prospective, Multi-Center PRostate Cancer Individual Signature Evaluation Trial (PReCISE) in Patients Undergoing Scheduled Prostate Biopsy CALGB 140602/ NCIC PR.11: A Phase III Study of Active Surveillance Therapy Against Radical Treatment In Patients Diagnosed With Favourable Risk Prostate Cancer (START) CALGB 70807: The Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance Pathologic Upstaging in Prostate Cancer Patients on Watchful Waiting Randomized, Multi-Institutional Trial of Ciprofloxacin versus Observation for Men with an Elevated Prostate Specific Antigen (PSA) Significance of Solitary Rib Abnormalities on Bone Scan for Clinically Localized or Biochemically Recurrent Prostate Cancer |
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| Mohan Gundeti | A Database of Patients Undergoing Surgery (Treatment) for Congenital Urological Anomalies Comparison of Ergonomics in Open, Laparoscopic, and Robotic Pyeloplasty Using a Porcine Model Pediatric Patients undergoing Robotic-Assisted Laparoscopic Surgery Pilot study of neurophysiologic recording and nerve identification during extra-vesical ureter-reimplantation |
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| Dennis Liu | Complex Lower Urinary Tract Reconstruction: A Comparative Study of Robotic-Assisted Laparoscopic Surgery Versus Open Surgery Does Ureteral Dilation Help Predict the Need for VCUG in the Evaluation of Hydronephrosis |
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| Arieh Shalhav | Clinical Care Pathway to Decrease Hospital Stay After Laparoscopic or Robotic Partial Nephrectomy: Factors Predictive for Success Clinical Urology Research Screening Protocol Minimally Invasive Renal Surgery: Multiinstitutional Experience of Patients Undergoing Laparoscopic and Robotic-Assisted Nephron Sparing Renal Surgery |
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| Gary Steinberg | A Multicenter, Randomized Placebo-Controlled, Double Blind, Phase 3 Trial of Single-Dose Intravesical EOquin as a Surgical Adjuvant Instilled in the Early Postoperative Period in Patients Undergoing Transurethral Resection for Noninvasive Bladder Cancer A Phase 1 Open Label Exploratory Study of an Autologous Neo-Urinary Conduit in Subjects Requiring Incontinent Urinary Diversion Following Radical Cystectomy A Phase 3, Randomized, Active-Controlled, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of EN3348 (MCC) as Compared with Mitomycin C in the Intravesical Treatment of Subjects with BCG Recurrent or Refractory Non-Muscle Invasive Bladder Cancer A Phase 4, Multicenter, Double-Blind, Placebo-Controlled, Parallel Study of Alvimopan for the Management of Postoperative Ileus in Subjects Undergoing Radical Cystectomy A Randomized Controlled Trial Assessing the Effects of a Post-operative Hospitalist Consult in Patients Undergoing Radical Cystectomy Bladder Cancer Sample Collection CALGB 9687: The Role of Salvage Prostatectomy for Radiation Failure In Prostate Carcinoma: A Phase II Trial Clinical Utility of The Vysis UroVysion Test and the Optimal Surveillance Strategies for Patients with Transitional Cell Carcinoma of the Bladder Detection of Bladder Cancer by Microsatellite Analysis (MSA) of Urinary Sediment: Multi-Institutional Study Evaluation of the UroVysion Test in Predicting Recurrence and/or Progression of Disease in Patients Receiving Initial BCG or BCG plus Interferon Therapy for Primary High Grade Papillary and CIS Urothelial Carcinoma of the Bladder Multi-Institutional Evaluation and Quality of Care Initiative for the Management of Muscle Invasive Bladder Cancer MVAC in Organ-Confined Bladder Cancer Based on p53 Status Normal Subject Urine Sample Collection Open-Label, Multi-Center Study of the Efficacy and Safety of MCC in the Treatment of Patients with Non-Muscle Invasive (Superficial) Bladder Cancer at High Risk of Progression and Who are Refractory to BCG Prospective Multi-Center Evaluation of High Grade T1 Bladder Cancer Protocol Quality of Life After Cystectomy |
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| Donald VanderGriend | Access to existing patient database to request archived tissue Acquisition of fresh and frozen tissue from urological surgical specimens |
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| Gregory Zagaja | Phase II, Randomized, Double-blind, Multi-centered Study of Polyphenon E in Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) and Atypical Small Acinar Proliferation (ASAP) Quality of Life After Radical Prostatectomy Randomized controlled trial of early removal of urethral catheter with suprapubic tube drainage versus urethral catheter drainage alone following robot-assisted laparoscopic radical prostatectomy Randomized Placebo-Controlled Adjuvant Study of Prevention of Prostate Cancer Recurrence After Radical Prostatectomy by Soy Protein Isolate Vitamin D levels and related genetic polymorphisms, sun exposure, skin color and risk of aggressive prostate cancer |
Vascular Surgery and Endovascular Therapy
Visit the Vascular Surgery research page for more information.
| Investigator | Title | Related Links |
|---|---|---|
| Christopher Skelly | Coronary angioplasty in Vascular patients Radiographic Characteristics of Carotid Plaque and Predictors of Symptomatic Disease Stenting and Angioplasty With Protection in Patients at High-Risk for Endarterectomy Structural and Molecular Determinants of Carotid Atherosclerotic Plaque Tissues Use of Saphenous Veins from Leg Amputations for ex vivo Intimal Hyperplasia Model Venous ex vivo Intimal Hyperplasia Model |
