Dr. Agrawal’s lab is devoted to the study of the genetics and molecular diagnostics of head and neck cancer. The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. His lab’s research is focused on the application of cancer genetics to design diagnostic approaches to reduce morbidity and mortality from head and neck cancer.
Memorial Sloan Kettering Cancer Center
New York, NY
Fellowship - Head and Neck Surgical Oncology
2008
Johns Hopkins University
Baltimore, MD
Post-doc - Molecular Genetics
2007
Johns Hopkins University
Baltimore, MD
Residency - Otolaryngology-Head and Neck Surgery
2007
Johns Hopkins University
Baltimore, MD
MD - Medicine
2001
Rutgers University
New Brunswick, NJ
BA - Biology
1997
Sensitive detection and quantification of SARS-CoV-2 in saliva.
Abasiyanik MF, Flood B, Lin J, Ozcan S, Rouhani SJ, Pyzer A, Trujillo J, Zhen C, Wu P, Jumic S, Wang A, Gajewski TF, Wang P, Hartley M, Ameti B, Niemiec R, Fernando M, Mishra V, Savage P, Aydogan B, Bethel C, Matushek S, Beavis KG, Agrawal N, Segal J, Tay S, Izumchenko E. Sensitive detection and quantification of SARS-CoV-2 in saliva. Sci Rep. 2021 06 14; 11(1):12425.
PMID: 34127708
Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
Wei T, Leisegang M, Xia M, Kiyotani K, Li N, Zeng C, Deng C, Jiang J, Harada M, Agrawal N, Li L, Qi H, Nakamura Y, Ren L. Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma. Oncoimmunology. 2021 May 25; 10(1):1929726.
PMID: 34104546
Radiation Therapy for Cutaneous Malignancies of the Head and Neck.
Katipally R, Agrawal N, Juloori A. Radiation Therapy for Cutaneous Malignancies of the Head and Neck. Otolaryngol Clin North Am. 2021 Apr; 54(2):307-327.
PMID: 33602518
Ultrasensitive detection of tumor-specific mutations in saliva of patients with oral cavity squamous cell carcinoma.
Shanmugam A, Hariharan AK, Hasina R, Nair JR, Katragadda S, Irusappan S, Ravichandran A, Veeramachaneni V, Bettadapura R, Bhati M, Ramaswamy V, Rao VUS, Bagadia RK, Manjunath A, Manjunath NML, Solomon MC, Maji S, Bahadur U, Bettegowda C, Papadopoulos N, Lingen MW, Hariharan R, Gupta V, Agrawal N, Izumchenko E. Ultrasensitive detection of tumor-specific mutations in saliva of patients with oral cavity squamous cell carcinoma. Cancer. 2021 May 15; 127(10):1576-1589.
PMID: 33405231
Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features.
Dolezal JM, Trzcinska A, Liao CY, Kochanny S, Blair E, Agrawal N, Keutgen XM, Angelos P, Cipriani NA, Pearson AT. Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. Mod Pathol. 2021 05; 34(5):862-874.
PMID: 33299111
Sensitive detection and quantification of SARS-CoV-2 in saliva.
Abasiyanik MF, Flood B, Lin J, Ozcan S, Rouhani SJ, Pyzer A, Trujillo J, Zhen C, Wu P, Jumic S, Wang A, Gajewski TF, Wang P, Hartley M, Ameti B, Niemiec R, Fernando M, Aydogan B, Bethel C, Matushek S, Beavis KG, Agrawal N, Segal J, Tay S, Izumchenko E. Sensitive detection and quantification of SARS-CoV-2 in saliva. medRxiv. 2020 Dec 07.
PMID: 33330880
The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma.
Campbell BR, Chen Z, Faden DL, Agrawal N, Li RJ, Hanna GJ, Iyer NG, Boot A, Rozen SG, Vettore AL, Panda B, Krishnan NM, Pickering CR, Myers JN, Guo X, Lang Kuhs KA. The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma. Cancer. 2021 Feb 15; 127(4):544-553.
PMID: 33146897
Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience.
Onderdonk BE, Vokes EE, Gwede M, Blair E, Agrawal N, Haraf DJ. Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience. Health Sci Rep. 2020 Dec; 3(4):e195.
PMID: 33043152
TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.
Sacconi A, Donzelli S, Pulito C, Ferrero S, Spinella F, Morrone A, Rigoni M, Pimpinelli F, Ensoli F, Sanguineti G, Pellini R, Agrawal N, Izumchenko E, Ciliberto G, Giannì A, Muti P, Strano S, Blandino G. TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients. J Exp Clin Cancer Res. 2020 Sep 23; 39(1):200.
PMID: 32967703
Status and strategies for the management of head and neck cancer during COVID-19 pandemic: Indian scenario.
Gupta A, Arora V, Nair D, Agrawal N, Su YX, Holsinger FC, Chan JYK. Status and strategies for the management of head and neck cancer during COVID-19 pandemic: Indian scenario. Head Neck. 2020 Jul; 42(7):1460-1465.
PMID: 32357281
Editorial Board
PLOS ONE
2019
AACR Team Science Award, American Association for Cancer Research
AACR
2017
Expert Panel, Early Detection (Screening) of Oral Cancer Clinical Practice Guidelines, American Dent
ADA
2016 - 2017
Reviewer (member)
NIH Cancer Genetics Study Section
2016
Senior Faculty Scholar, Bucksbaum Institute for Clinical Excellence
University of Chicago
2016
Editorial Board
Scientific Reports
2015
George T Nager Award for Excellence in Teaching
Johns Hopkins University
2012
Owsei Temkin Scholarship
Johns Hopkins University
2001
Richard Westcott Appleton Scholarship
Johns Hopkins University
2001
Johns Hopkins University School of Medicine Scholarship
Johns Hopkins University
1999
Marvin Harold Cheiten Award (1st in class), Rutgers University
Rutgers University
1997