Dr. Agrawal’s lab is devoted to the study of the genetics and molecular diagnostics of head and neck cancer. The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. His lab’s research is focused on the application of cancer genetics to design diagnostic approaches to reduce morbidity and mortality from head and neck cancer.
Memorial Sloan Kettering Cancer Center
New York, NY
Fellowship - Head and Neck Surgical Oncology
2008
Johns Hopkins University
Baltimore, MD
Post-doc - Molecular Genetics
2007
Johns Hopkins University
Baltimore, MD
Residency - Otolaryngology-Head and Neck Surgery
2007
Johns Hopkins University
Baltimore, MD
MD - Medicine
2001
Rutgers University
New Brunswick, NJ
BA - Biology
1997
PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands.
PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands. J Exp Clin Cancer Res. 2025 Jan 11; 44(1):11.
PMID: 39794830
Circulating tumor DNA in head and neck squamous cell carcinoma-current status and future prospects.
Circulating tumor DNA in head and neck squamous cell carcinoma-current status and future prospects. Acad Oncol. 2024; 1(2).
PMID: 39867572
A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors.
A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors. Neuro Oncol. 2024 Oct 03; 26(10):1895-1911.
PMID: 38981018
Neoadjuvant Nivolumab Plus Chemotherapy Followed By Response-Adaptive Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Controlled Trial.
Neoadjuvant Nivolumab Plus Chemotherapy Followed By Response-Adaptive Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Controlled Trial. JAMA Oncol. 2024 Jul 01; 10(7):923-931.
PMID: 38842838
Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer.
Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer. NPJ Precis Oncol. 2024 May 23; 8(1):114.
PMID: 38783041
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma. Cell Rep. 2024 03 26; 43(3):113826.
PMID: 38412093
Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma.
Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma. Oral Oncol. 2024 Feb; 149:106688.
PMID: 38219706
Inflammatory Tongue Conditions and Risk of Oral Tongue Cancer Among the US Elderly Individuals.
Inflammatory Tongue Conditions and Risk of Oral Tongue Cancer Among the US Elderly Individuals. J Clin Oncol. 2024 May 20; 42(15):1745-1753.
PMID: 38033283
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging. Aging Cell. 2023 12; 22(12):e14017.
PMID: 37888486
The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring.
The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring. Cell Rep Med. 2023 10 17; 4(10):101198.
PMID: 37716353
Editorial Board
PLOS ONE
2019
AACR Team Science Award, American Association for Cancer Research
AACR
2017
Expert Panel, Early Detection (Screening) of Oral Cancer Clinical Practice Guidelines, American Dent
ADA
2016 - 2017
Reviewer (member)
NIH Cancer Genetics Study Section
2016
Senior Faculty Scholar, Bucksbaum Institute for Clinical Excellence
University of Chicago
2016
Editorial Board
Scientific Reports
2015
George T Nager Award for Excellence in Teaching
Johns Hopkins University
2012
Owsei Temkin Scholarship
Johns Hopkins University
2001
Richard Westcott Appleton Scholarship
Johns Hopkins University
2001
Johns Hopkins University School of Medicine Scholarship
Johns Hopkins University
1999
Marvin Harold Cheiten Award (1st in class), Rutgers University
Rutgers University
1997