Dr. Agrawal’s lab is devoted to the study of the genetics and molecular diagnostics of head and neck cancer. The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. His lab’s research is focused on the application of cancer genetics to design diagnostic approaches to reduce morbidity and mortality from head and neck cancer.
Memorial Sloan Kettering Cancer Center
New York, NY
Fellowship - Head and Neck Surgical Oncology
2008
Johns Hopkins University
Baltimore, MD
Post-doc - Molecular Genetics
2007
Johns Hopkins University
Baltimore, MD
Residency - Otolaryngology-Head and Neck Surgery
2007
Johns Hopkins University
Baltimore, MD
MD - Medicine
2001
Rutgers University
New Brunswick, NJ
BA - Biology
1997
Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features.
Dolezal JM, Trzcinska A, Liao CY, Kochanny S, Blair E, Agrawal N, Keutgen XM, Angelos P, Cipriani NA, Pearson AT. Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. Mod Pathol. 2020 Dec 10.
PMID: 33299111
Sensitive detection and quantification of SARS-CoV-2 in saliva.
Abasiyanik MF, Flood B, Lin J, Ozcan S, Rouhani SJ, Pyzer A, Trujillo J, Zhen C, Wu P, Jumic S, Wang A, Gajewski TF, Wang P, Hartley M, Ameti B, Niemiec R, Fernando M, Aydogan B, Bethel C, Matushek S, Beavis KG, Agrawal N, Segal J, Tay S, Izumchenko E. Sensitive detection and quantification of SARS-CoV-2 in saliva. medRxiv. 2020 Dec 07.
PMID: 33330880
The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma.
Campbell BR, Chen Z, Faden DL, Agrawal N, Li RJ, Hanna GJ, Iyer NG, Boot A, Rozen SG, Vettore AL, Panda B, Krishnan NM, Pickering CR, Myers JN, Guo X, Lang Kuhs KA. The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma. Cancer. 2020 Nov 04.
PMID: 33146897
Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience.
Onderdonk BE, Vokes EE, Gwede M, Blair E, Agrawal N, Haraf DJ. Adjuvant treatment for high-risk salivary gland malignancies and prognostic stratification based on a 20-year single institution experience. Health Sci Rep. 2020 Dec; 3(4):e195.
PMID: 33043152
TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.
Sacconi A, Donzelli S, Pulito C, Ferrero S, Spinella F, Morrone A, Rigoni M, Pimpinelli F, Ensoli F, Sanguineti G, Pellini R, Agrawal N, Izumchenko E, Ciliberto G, Giannì A, Muti P, Strano S, Blandino G. TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients. J Exp Clin Cancer Res. 2020 Sep 23; 39(1):200.
PMID: 32967703
Status and strategies for the management of head and neck cancer during COVID-19 pandemic: Indian scenario.
Gupta A, Arora V, Nair D, Agrawal N, Su YX, Holsinger FC, Chan JYK. Status and strategies for the management of head and neck cancer during COVID-19 pandemic: Indian scenario. Head Neck. 2020 Jul; 42(7):1460-1465.
PMID: 32357281
A Surgical Safety Checklist for Performing Tracheotomy in Patients with Coronavirus Disease 19.
Portugal LG, Adams DR, Baroody FM, Agrawal N. A Surgical Safety Checklist for Performing Tracheotomy in Patients with Coronavirus Disease 19. Otolaryngol Head Neck Surg. 2020 07; 163(1):42-46.
PMID: 32340546
Dose and Volume De-Escalation for Human Papillomavirus-Positive Oropharyngeal Cancer is Associated with Favorable Posttreatment Functional Outcomes.
Foster CC, Seiwert TY, MacCracken E, Blair EA, Agrawal N, Melotek JM, Portugal L, Brisson RJ, Gooi Z, Spiotto MT, Vokes EE, Haraf DJ. Dose and Volume De-Escalation for Human Papillomavirus-Positive Oropharyngeal Cancer is Associated with Favorable Posttreatment Functional Outcomes. Int J Radiat Oncol Biol Phys. 2020 Jul 15; 107(4):662-671.
PMID: 32311416
Medically Necessary, Time-Sensitive Procedures: Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic.
Prachand VN, Milner R, Angelos P, Posner MC, Fung JJ, Agrawal N, Jeevanandam V, Matthews JB. Medically Necessary, Time-Sensitive Procedures: Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic. J Am Coll Surg. 2020 Aug; 231(2):281-288.
PMID: 32278725
Novel Strategies to Effectively De-escalate Curative-Intent Therapy for Patients With HPV-Associated Oropharyngeal Cancer: Current and Future Directions.
Price KAR, Nichols AC, Shen CJ, Rammal A, Lang P, Palma DA, Rosenberg AJ, Chera BS, Agrawal N. Novel Strategies to Effectively De-escalate Curative-Intent Therapy for Patients With HPV-Associated Oropharyngeal Cancer: Current and Future Directions. Am Soc Clin Oncol Educ Book. 2020 Mar; 40:1-13.
PMID: 32213088
Editorial Board
PLOS ONE
2019
AACR Team Science Award, American Association for Cancer Research
AACR
2017
Expert Panel, Early Detection (Screening) of Oral Cancer Clinical Practice Guidelines, American Dent
ADA
2016 - 2017
Reviewer (member)
NIH Cancer Genetics Study Section
2016
Senior Faculty Scholar, Bucksbaum Institute for Clinical Excellence
University of Chicago
2016
Editorial Board
Scientific Reports
2015
George T Nager Award for Excellence in Teaching
Johns Hopkins University
2012
Owsei Temkin Scholarship
Johns Hopkins University
2001
Richard Westcott Appleton Scholarship
Johns Hopkins University
2001
Johns Hopkins University School of Medicine Scholarship
Johns Hopkins University
1999
Marvin Harold Cheiten Award (1st in class), Rutgers University
Rutgers University
1997